Zika virus degrades the ω-3 fatty acid transporter Mfsd2a in brain microvascular endothelial cells and impairs lipid homeostasis
Identifieur interne : 000266 ( Main/Exploration ); précédent : 000265; suivant : 000267Zika virus degrades the ω-3 fatty acid transporter Mfsd2a in brain microvascular endothelial cells and impairs lipid homeostasis
Auteurs : Jia Zhou [République populaire de Chine] ; Xiaojing Chi [République populaire de Chine] ; Min Cheng [République populaire de Chine] ; Xingyao Huang [République populaire de Chine] ; Xiuying Liu [République populaire de Chine] ; Jingjing Fan [République populaire de Chine] ; Hua Xu [République populaire de Chine] ; Tianli Lin [République populaire de Chine] ; Lei Shi [République populaire de Chine] ; Chengfeng Qin [République populaire de Chine] ; Wei Yang [République populaire de Chine]Source :
- Science Advances [ 2375-2548 ] ; 2019.
Abstract
Both the endothelial transporter Mfsd2a and docosahexaenoic acid uptake are disrupted in Zika virus–induced microcephaly models.
Url:
DOI: 10.1126/sciadv.aax7142
PubMed: 31681849
PubMed Central: 6810275
Affiliations:
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